01 AUG 2026CPE
Price concession £2.11 for pack size 28
START DATE AS PUBLISHED BY THE SOURCE · APPLIES IN ENG
cpe.org.uk · PUBLISHED 28 AUG 2026
Bisoprolol 1.25mg tablets
VMP 42371111000001100 · TABLETS · 1.25MG
NAME FROM dm+d 7.3.0__F_VMP2_3230726.XML · THE CODE IS THE IDENTITY
TIER LADDERA TIER IS A GOVERNMENT ACT, NOT OUR OPINION. EVERY RUNG NAMES THE ACT THAT PUTS IT IN FORCE.
WATCHNOT IN FORCEMEDICINE SUPPLY NOTIFICATION IN FORCE · DHSC
CONCERNNOT IN FORCELISTED ON THE RESTRICTED MEDICINES (PARALLEL-EXPORT / HOARDING) LIST · DHSC / MHRA
CRITICALNOT IN FORCESERIOUS SHORTAGE PROTOCOL IN FORCE · NHSBSA
NO RUNG IS IN FORCE FOR THIS MEDICINE. A PRICE CONCESSION IS NOT A RUNG — IT IS A SIGNAL, AND SIGNALS NEVER MOVE A TIER.
SIGNALS
SLIPPAGEn/aSSP expiry revisions — a Serious Shortage Protocol re-dated to a later expiry, the earliest honest sign a shortage is lasting longer than first stated. One row per revision (prior_date → revised_date, signed slip_days), published at /api/v1/slippage.json. Computed from the append-only ledger, which keeps every expiry as its own immutable observation.
MARKET STRESSn/aPrice-concession presence and month-on-month movement. Concession churn often runs ahead of formal notices.
DURATION PERCENTILESn/aHistorical resolution times for comparable shortages. Computed from accumulated history, never predicted.
CRITICALITY WHO EMLn/aPresence on the WHO Model List of Essential Medicines.
CRITICALITY EU CRITICALn/aPresence on the EU Union list of critical medicines. Published independently of WHO EML — where the two disagree, the disagreement is displayed rather than resolved.
CROSS JURISDICTION STRESSn/aCount of other regulators reporting a shortage of the same MOLECULE. Reported at molecule level via ATC/INN — never implying product equivalence across jurisdictions.
EVERY SIGNAL IS DEFINED IN THE PUBLISHED CONTRACT. MARKET STRESS IS COMPUTED WHERE A TIER IS IN FORCE; THE OTHERS ARE NOT COMPUTED YET AND READ n/a RATHER THAN ZERO — A ZERO WOULD CLAIM WE MEASURED.
PRESCRIBING VOLUME — ENGLAND704,887ITEMS · JUN 2026 · NHSBSA EPD
NHS CENTRAL EAST INTEGRATED CARE BOARDS1Y5D41,151
NHS WEST AND NORTH LONDON INTEGRATED CARE BOARDZ9B2Z39,903
NHS NORTH EAST AND NORTH CUMBRIA INTEGRATED CARE BOARDQHM39,812
NHS SURREY AND SUSSEX INTEGRATED CARE BOARDS9B9J39,188
NHS GREATER MANCHESTER INTEGRATED CARE BOARDQOP37,363
NHS CHESHIRE AND MERSEYSIDE INTEGRATED CARE BOARDQYG35,985
NHS WEST YORKSHIRE INTEGRATED CARE BOARDQWO27,507
NHS NORFOLK AND SUFFOLK INTEGRATED CARE BOARDT6Y0W26,199
TOP 8 OF 37 ICBS BY VOLUME. ONE MONTH ONLY — NOT A TREND. FULL BREAKDOWN IN DEMAND.JSON.
SAME-VTM SIBLINGS
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
186,308 ITEMS
1,052,001 ITEMS
119,023 ITEMS
540,579 ITEMS
79,530 ITEMS
325 ITEMS
2 ITEMS
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
NO EPD ROW
SAME VTM IN dm+d — A CLASSIFICATION FACT, NOT A SUBSTITUTION RECOMMENDATION. LINKED ONLY WHERE PHARMASYNC HOLDS A RECORD FOR THAT CODE.
1 RECORD · SINCE 01 AUG 2026LEFT = ACT, RIGHT = PUBLISHER
EVERY RECORD PHARMASYNC HOLDS FOR THIS MEDICINE IS ABOVE — THE LEDGER IS APPEND-ONLY, SO A REVISION APPEARS AS A FURTHER RECORD RATHER THAN AN EDIT. DATA AS OF 11:42 · 15 SEP 2026.
SUBSTITUTION AND DOSING SIT WITH — OPEN SPS